Convenient method for the preparation of 2′-deoxyribosylurea by thymidine oxidation and NMR study of both anomers

被引：13

作者：

Dubey, I ^{[1
]}

Pratviel, G ^{[1
]}

Robert, A ^{[1
]}

Meunier, B ^{[1
]}

机构：

[1] CNRS, Chim Coordinat Lab, F-31077 Toulouse 4, France

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2001年 / 20卷 / 08期

关键词：

D O I：

10.1081/NCN-100105241

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis of 2 ' -deoxyribosylurea by thymidine oxidation with potassium permanganate followed, by alkaline hydrolysis of intermediates is described. The anomeric configuration of the resulting products was studied by NMR spectroscopy.

引用

页码：1463 / 1471

页数：9

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