Modular chiral selenium-containing oxazolines:: synthesis and application in the palladium-catalyzed asymmetric allylic alkylation

被引：64

作者：

Braga, AL ^{[1
]}

Lüdtke, DS ^{[1
]}

Sehnem, JA ^{[1
]}

Alberto, EE ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

来源：

TETRAHEDRON | 2005年 / 61卷 / 49期

关键词：

selenium; catalyst; oxazolines; ligands;

D O I：

10.1016/j.tet.2005.09.044

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new series of modular chiral selenium-containing oxazolines has been synthesized from inexpensive and commercially available L-serine and L-aspartic acid. These new compounds were evaluated as chiral ligands in the palladium-catalyzed asymmetric allylic alkylation reaction, furnishing the product in high enantiomeric excess, using CS2CO3/CH2Cl2 as the base/solvent system. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：11664 / 11671

页数：8

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