Emerging role for transcript elongation in plant development

被引:18
作者
Grasser, KD [1 ]
机构
[1] Aalborg Univ, Dept Life Sci, DK-9000 Aalborg, Denmark
关键词
D O I
10.1016/j.tplants.2005.08.004
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Transcript elongation by RNA polymerase II (RNAPII), once regarded as the simple extension of the initiated mRNA, is a complex and highly regulated phase of the transcription cycle. Many factors have been identified that contribute to the dynamic control of the elongation stage of transcription. There are elongation factors that modulate the activity of RNAPII and other factors that facilitate the transcription through chromatin. Recent studies of mutants defective in elongation factors have revealed the importance of proper transcript elongation for the development of higher eukaryotes. Here, the essentials of transcript elongation are briefly summarized to discuss its role in developmental processes.
引用
收藏
页码:484 / 490
页数:7
相关论文
共 62 条
[1]   Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS [J].
Adelman, K ;
Marr, MT ;
Werner, J ;
Saunders, A ;
Ni, ZY ;
Andrulis, ED ;
Lis, JT .
MOLECULAR CELL, 2005, 17 (01) :103-112
[2]   The dynamic machinery of mRNA elongation [J].
Armache, KJ ;
Kettenberger, H ;
Cramer, P .
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2005, 15 (02) :197-203
[3]   ENHANCEMENT OF HUMAN ESTROGEN-RECEPTOR ACTIVITY BY SPT6 - A POTENTIAL COACTIVATOR [J].
BANIAHMAD, C ;
NAWAZ, Z ;
BANIAHMAD, A ;
GLEESON, MAG ;
TSAI, MJ ;
OMALLEY, BW .
MOLECULAR ENDOCRINOLOGY, 1995, 9 (01) :34-43
[4]   Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes [J].
Bannister, AJ ;
Schneider, R ;
Myers, FA ;
Thorne, AW ;
Crane-Robinson, C ;
Kouzarides, T .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (18) :17732-17736
[5]   Vernalization requires epigenetic silencing of FLC by histone methylation [J].
Bastow, R ;
Mylne, JS ;
Lister, C ;
Lippman, Z ;
Martienssen, RA ;
Dean, C .
NATURE, 2004, 427 (6970) :164-167
[6]   FACT facilitates transcription-dependent nucleosome alteration [J].
Belotserkovskaya, R ;
Oh, S ;
Bondarenko, VA ;
Orphanides, G ;
Studitsky, VM ;
Reinberg, D .
SCIENCE, 2003, 301 (5636) :1090-1093
[7]   Exploring functional relationships between components of the gene expression machinery [J].
Burckin, T ;
Nagel, R ;
Mandel-Gutfreund, Y ;
Shiue, L ;
Clark, TA ;
Chong, JL ;
Chang, TH ;
Squazzo, S ;
Hartzog, G ;
Ares, M .
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2005, 12 (02) :175-182
[8]   The high-mobility-group box protein SSRP1/T160 is essential for cell viability in day 3.5 mouse embryos [J].
Cao, S ;
Bendall, H ;
Hicks, GG ;
Nashabi, A ;
Sakano, H ;
Shinkai, Y ;
Gariglio, M ;
Oltz, EA ;
Ruley, HE .
MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (15) :5301-5307
[9]   Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation [J].
Corey, LL ;
Weirich, CS ;
Benjamin, IJ ;
Kingston, RE .
GENES & DEVELOPMENT, 2003, 17 (11) :1392-1401
[10]   The chromatin remodelling complex FACT associates with actively transcribed regions of the Arabidopsis genome [J].
Duroux, M ;
Houben, A ;
Ruzicka, K ;
Friml, J ;
Grasser, KD .
PLANT JOURNAL, 2004, 40 (05) :660-671