Highly Efficient Continuous Flow Reactions Using Singlet Oxygen as a "Green" Reagent

被引：176

作者：

Levesque, Francois

Seeberger, Peter H. ^{[1
]}

机构：

[1] Max Planck Inst Colloids & Interfaces, Dept Biomol Syst, D-14476 Potsdam, Germany

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 19期

关键词：

2-PHASE FLOW; GENERATION; GLYCOSYLATION; DEACTIVATION; OPTIMIZATION;

D O I：

10.1021/ol2017643

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Described is a new method for the efficient in situ production of singlet oxygen in a simple continuous flow photochemical reactor. The extremely large interfacial area generated by running the biphasic mixture in a narrow channel at a high flow rate ensures high throughput as well as fast and efficient oxidation of various alkenes, 1,3-dienes, and thioethers on a preparative scale.

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页码：5008 / 5011

页数：4

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