Characterization of IS6110 restriction fragment length polymorphism patterns and mechanisms of antimicrobial resistance for multidrug-resistant isolates of Mycobacterium tuberculosis from a major reference hospital in Assiut, Egypt

被引:18
作者
Abbadi, S
Rashed, HG
Morlock, GP
Woodley, CL
El Shanawy, O
Cooksey, RC
机构
[1] Ctr Dis Control & Prevent, TB Mycobacteriol Branch, Div AIDS STD & TB Lab Res, Natl Ctr Infect Dis, Atlanta, GA 30333 USA
[2] Assiut Univ Hosp, Assiut, Egypt
关键词
D O I
10.1128/JCM.39.6.2330-2334.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We evaluated 25 Mycobacterium tuberculosis isolates from patients at a major Egyptian reference hospital in Assiut, Egypt, who had been treated for at least 1 year for tuberculosis. Typing patterns (IS6110) were diverse, and multidrug resistance mas found among 11 (44%) of the isolates. Mutations associated with antimicrobial drag resistance were found in rpoB, katG, rpsL, and embB in the resistant isolates.
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收藏
页码:2330 / 2334
页数:5
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