Mutations of the Notch1 gene in T-cell acute lymphoblastic leukemia: analysis in adults and children

被引：50

作者：

Lee, SY

Kumano, K

Masuda, S

Hangaishi, A

Takita, J

Nakazaki, K

Kurokawa, M

Hayashi, Y

Ogawa, S

Chiba, S

机构：

[1] Univ Tokyo, Dept Cell Therapy & Transplantat Med, Tokyo, Japan

[2] Univ Tokyo, Dept Hematol & Oncol, Tokyo, Japan

[3] Univ Tokyo, Dept Regenerat Med Hematopoiesis, Tokyo, Japan

[4] Univ Tokyo, Dept Pediat, Tokyo, Japan

[5] Gunma Childrens Med Ctr, Dept Hematol & Oncol, Gunma, Japan

来源：

LEUKEMIA | 2005年 / 19卷 / 10期

关键词：

D O I：

10.1038/sj.leu.2403896

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1841 / 1843

页数：4

共 8 条

[1] Adults are not simply big children [J].

Aplan, PD .

BLOOD, 2004, 103 (07) :2437-2438

[2] Notch signaling: Cell fate control and signal integration in development [J].

Artavanis-Tsakonas, S ;

Rand, MD ;

Lake, RJ .

SCIENCE, 1999, 284 (5415) :770-776

[3]

Hoelzer D, 2000, SEMIN ONCOL, V27, P540

[4] LOSS OF THE CYCLIN-DEPENDENT KINASE 4-INHIBITOR (P16-MTS1) GENE IS FREQUENT IN AND HIGHLY SPECIFIC TO LYMPHOID TUMORS IN PRIMARY HUMAN HEMATOPOIETIC MALIGNANCIES [J].

OGAWA, S ;

HANGAISHI, A ;

MIYAWAKI, S ;

HIROSAWA, S ;

MIURA, Y ;

TAKEYAMA, K ;

KAMADA, N ;

OHTAKE, S ;

UIKE, N ;

SHIMAZAKI, C ;

TOYAMA, K ;

HIRANO, M ;

MIZOGUCHI, H ;

KOBAYASHI, Y ;

FURUSAWA, S ;

SAITO, M ;

EMI, N ;

YAZAKI, Y ;

UEDA, R ;

HIRAI, H .

BLOOD, 1995, 86 (04) :1548-1556

[5] The role of Notch in tumorigenesis: Oncogene or tumour suppressor? [J].

Radtke, F ;

Raj, K .

NATURE REVIEWS CANCER, 2003, 3 (10) :756-767

[6] Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia [J].

Weng, AP ;

Ferrando, AA ;

Lee, W ;

Morris, JP ;

Silverman, LB ;

Sanchez-Irizarry, C ;

Blacklow, SC ;

Look, AT ;

Aster, JC .

SCIENCE, 2004, 306 (5694) :269-271

[7] Therapeutic strategies for Alzheimer's disease [J].

Wolfe, MS .

NATURE REVIEWS DRUG DISCOVERY, 2002, 1 (11) :859-866

[8] Chronic treatment with the γ-secretase inhibitor LY-411,575 inhibits β-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation [J].

Wong, GT ;

Manfra, D ;

Poulet, FM ;

Zhang, Q ;

Josien, H ;

Bara, T ;

Engstrom, L ;

Pinzon-Ortiz, M ;

Fine, JS ;

Lee, HJJ ;

Zhang, LL ;

Higgins, GA ;

Parker, EM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (13) :12876-12882

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