Pathway information for systems biology

被引：86

作者：

Cary, MP ^{[1
]}

Bader, GD ^{[1
]}

Sander, C ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Computat Biol Ctr, New York, NY 10021 USA

来源：

FEBS LETTERS | 2005年 / 579卷 / 08期

关键词：

pathway data integration; pathway database; standard exchange format; ontology; information system;

D O I：

10.1016/j.febslet.2005.02.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Pathway information is vital for successful quantitative modeling of biological systems. The almost 170 online pathway databases vary widely in coverage and representation of biological processes, making their use extremely difficult. Future pathway information systems for querying, visualization and analysis must support standard exchange formats to successfully integrate data on a large scale. Such integrated systems will greatly facilitate the constructive cycle of computational model building and experimental verification that lies at the heart of systems biology. (c) 2005 Federation of European Biochemical Societies. Published by, Elsevier B.V. All rights reserved.

引用

页码：1815 / 1820

页数：6

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