Y-maze avoidance: An automated and rapid associative learning paradigm in zebrafish

被引：39

作者：

Aoki, Ryo ^{[1
,2
]}

Tsuboi, Takashi ^{[2
]}

Okamoto, Hitoshi ^{[1
]}

机构：

[1] RIKEN, Brain Sci Inst, Lab Dev Gene Regulat, Neural Growth & Regenerat Res Grp, Wako, Saitama 3510198, Japan

[2] Univ Tokyo, Grad Sch Arts & Sci, Dept Life Sci, Meguro Ku, Tokyo 1538902, Japan

来源：

NEUROSCIENCE RESEARCH | 2015年 / 91卷

关键词：

Adult zebrafish; Aversive learning paradigm; MATLAB; Automated position detection; DANIO-RERIO; MEMORY FUNCTION; INVOLVEMENT; PREFERENCE; FOREBRAIN;

D O I：

10.1016/j.neures.2014.10.012

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Adult zebrafish are gaining attention in behavioral neuroscience. By combining video tracking and computer-controlled visual cue presentations on a liquid crystal display screen under the tank, we have developed a new method by which zebrafish can be trained to avoid one arm of a Y-shaped tank by presenting a specific color on the floor paired with an electric shock. Within two hours, zebrafish learn to choose the correct arm at an efficiency of 89.0%. In addition, we also developed a graphical user interface to modify the paradigm assessment parameters such as shape of the tank and time schedules. (C) 2014 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

引用

页码：69 / 72

页数：4

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