An update on Middle East respiratory syndrome: 2 years later

被引:16
作者
Al-Tawfiq, Jaffar A. [1 ,2 ]
Memish, Ziad A. [3 ,4 ]
机构
[1] Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia
[2] Indiana Univ Sch Med, Indianapolis, IN 46202 USA
[3] Minist Hlth, Riyadh 11176, Saudi Arabia
[4] Alfaisal Univ, Riyadh 11176, Saudi Arabia
关键词
coronavirus; MERS-CoV; Middle East respiratory syndrome; SYNDROME CORONAVIRUS INFECTION; RECEPTOR-BINDING DOMAIN; TO-HUMAN TRANSMISSION; HEALTH-CARE WORKER; MERS-CORONAVIRUS; SAUDI-ARABIA; NEUTRALIZING ANTIBODIES; DROMEDARY CAMELS; SPIKE PROTEIN; TRACT INFECTIONS;
D O I
10.1586/17476348.2015.1027689
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Middle East respiratory syndrome coronavirus (MERS-CoV) was first recognized in 2012 and since then has resulted in cases in 23 countries in four continents. The majority of these cases were reported from the Kingdom of Saudi Arabia. The disease caused a spectrum of illness, from asymptomatic to severe and possibly fatal disease. Recent studies showed that the transmission of MERS-CoV among family contacts remains relatively low. Currently, there are no approved vaccines or therapeutics for MERS-CoV.
引用
收藏
页码:327 / 335
页数:9
相关论文
共 82 条
[1]   Investigation of Anti-Middle East Respiratory Syndrome Antibodies in Blood Donors and Slaughterhouse Workers in Jeddah and Makkah, Saudi Arabia, Fall 2012 [J].
Aburizaiza, Asad S. ;
Mattes, Frank M. ;
Azhar, Esam I. ;
Hassan, Ahmed M. ;
Memish, Ziad A. ;
Muth, Doreen ;
Meyer, Benjamin ;
Lattwein, Erik ;
Mueller, Marcel A. ;
Drosten, Christian .
JOURNAL OF INFECTIOUS DISEASES, 2014, 209 (02) :243-246
[2]   Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels [J].
Adney, Danielle R. ;
van Doremalen, Neeltje ;
Brown, Vienna R. ;
Bushmaker, Trenton ;
Scott, Dana ;
de Wit, Emmie ;
Bowen, Richard A. ;
Munster, Vincent J. .
EMERGING INFECTIOUS DISEASES, 2014, 20 (12) :1999-2005
[3]   Hospital-Associated Outbreak of Middle East Respiratory Syndrome Coronavirus: A Serologic, Epidemiologic, and Clinical Description [J].
Al-Abdallat, Mohammad Mousa ;
Payne, Daniel C. ;
Alqasrawi, Sultan ;
Rha, Brian ;
Tohme, Rania A. ;
Abedi, Glen R. ;
Al Nsour, Mohannad ;
Iblan, Ibrahim ;
Jarour, Najwa ;
Farag, Noha H. ;
Haddadin, Aktham ;
Al-Sanouri, Tarek ;
Tamin, Azaibi ;
Harcourt, Jennifer L. ;
Kuhar, David T. ;
Swerdlow, David L. ;
Erdman, Dean D. ;
Pallansch, Mark A. ;
Haynes, Lia M. ;
Gerber, Susan I. .
CLINICAL INFECTIOUS DISEASES, 2014, 59 (09) :1225-1233
[4]   Middle East respiratory syndrome coronavirus: epidemiology and disease control measures [J].
Al-Tawfiq, Jaffar A. ;
Memish, Ziad A. .
INFECTION AND DRUG RESISTANCE, 2014, 7 :281-287
[5]   Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution [J].
Al-Tawfiq, Jaffar A. ;
Memish, Ziad A. .
TRENDS IN MICROBIOLOGY, 2014, 22 (10) :573-579
[6]   Travel implications of emerging coronaviruses: SARS and MERS-CoV [J].
Al-Tawfiq, Jaffar A. ;
Zumla, Alimuddin ;
Memish, Ziad A. .
TRAVEL MEDICINE AND INFECTIOUS DISEASE, 2014, 12 (05) :422-428
[7]   Coronaviruses: severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus in travelers [J].
Al-Tawfiq, Jaffar A. ;
Zumla, Alimuddin ;
Memish, Ziad A. .
CURRENT OPINION IN INFECTIOUS DISEASES, 2014, 27 (05) :411-417
[8]   Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study [J].
Al-Tawfiq, Jaffar A. ;
Momattin, Hisham ;
Dib, Jean ;
Memish, Ziad A. .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2014, 20 :42-46
[9]   Middle East Respiratory Syndrome Coronavirus Antibody Reactors Among Camels in Dubai, United Arab Emirates, in 2005 [J].
Alexandersen, S. ;
Kobinger, G. P. ;
Soule, G. ;
Wernery, U. .
TRANSBOUNDARY AND EMERGING DISEASES, 2014, 61 (02) :105-108
[10]  
Ali MT, 2014, BIOINFORMATION, V10, P533, DOI 10.6026/97320630010533