A Toll-like trigger for autoimmune disease

被引：15

作者：

Bach, JF ^{[1
]}

机构：

[1] Inst Natl Sante & Rech Med, F-75015 Paris, France

来源：

NATURE MEDICINE | 2005年 / 11卷 / 02期

关键词：

D O I：

10.1038/nm0205-120

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Autoimmune disease is set in motion by certain triggers, one of which now comes to light in a mouse model of type 1 diabetes. Signaling through Toll-like receptors, known for receiving signals from viruses and bacteria, initiates the disease (pages 138-145).

引用

页码：120 / 121

页数：2

共 15 条

[11] T cell clones to epitopes of glutamic acid decarboxylase 65 raised from normal subjects and patients with insulin-dependent diabetes [J].