Activity of telithromycin against penicillin-resistant Streptococcus pneumoniae isolates recovered from French children with invasive and noninvasive infections

被引：5

作者：

Bingen, E

Doit, C

Loukil, C

Brahimi, N

Bidet, P

Deforche, D

Geslin, P

机构：

[1] Hop Robert Debre, Microbiol Serv, F-75019 Paris, France

[2] Hop Intercommunal Creteil, Microbiol Serv, Creteil, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2003年 / 47卷 / 07期

关键词：

D O I：

10.1128/AAC.47.7.2345-2347.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We compared the activities of telithromycin, erythromycin, azithromycin, josamycin, penicillin G, amoxicillin, cefpodoxime, and ceftriaxone against invasive and noninvasive non-penicillin-susceptible Streptococcus pneumoniae isolates recovered from children. Of the 186 isolates tested, 89% were positive for erm(B) by PCR. Telithromycin had the lowest MICs, with MICs at which 90% of the isolates tested are inhibited of 0.032 and 0.25 mug/ml for erythromycin-sensitive and -resistant isolates, respectively.

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页码：2345 / 2347

页数：3

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