Overview of the CCP4 suite and current developments

被引：10410

作者：

Winn, Martyn D. ^{[1
]}

Ballard, Charles C. ^{[2
]}

Cowtan, Kevin D. ^{[3
]}

Dodson, Eleanor J. ^{[3
]}

Emsley, Paul ^{[4
]}

Evans, Phil R. ^{[5
]}

Keegan, Ronan M. ^{[2
]}

Krissinel, Eugene B. ^{[2
]}

Leslie, Andrew G. W. ^{[5
]}

McCoy, Airlie ^{[6
]}

McNicholas, Stuart J. ^{[3
]}

Murshudov, Garib N. ^{[3
]}

Pannu, Navraj S. ^{[7
]}

Potterton, Elizabeth A. ^{[3
]}

Powell, Harold R. ^{[5
]}

Read, Randy J. ^{[6
]}

Vagin, Alexei ^{[3
]}

Wilson, Keith S. ^{[3
]}

机构：

[1] STFC Daresbury Lab, Warrington WA4 4AD, Cheshire, England

[2] STFC Rutherford Appleton Lab, Didcot OX11 0QX, Oxon, England

[3] Univ York, Dept Chem, York Struct Biol Lab, York YO10 5YW, N Yorkshire, England

[4] Univ Oxford, Dept Biochem, Oxford OX1 3QU, England

[5] MRC, Mol Biol Lab, Cambridge CB2 0QH, England

[6] Univ Cambridge, Dept Haematol, Cambridge Inst Med Res, Cambridge CB2 2XY, England

[7] Leiden Univ, NL-2300 RA Leiden, Netherlands

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY | 2011年 / 67卷

基金：

英国惠康基金; 英国生物技术与生命科学研究理事会; 英国医学研究理事会;

关键词：

MACROMOLECULAR STRUCTURES; MOLECULAR-REPLACEMENT; PHASE INFORMATION; CRYSTALLOGRAPHY; REFINEMENT; KNOWLEDGE; SOFTWARE; EXAMPLES; PROGRAM; MOLREP;

D O I：

10.1107/S0907444910045749

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The CCP4 (Collaborative Computational Project, Number 4) software suite is a collection of programs and associated data and software libraries which can be used for macromolecular structure determination by X-ray crystallography. The suite is designed to be flexible, allowing users a number of methods of achieving their aims. The programs are from a wide variety of sources but are connected by a common infrastructure provided by standard file formats, data objects and graphical interfaces. Structure solution by macromolecular crystallography is becoming increasingly automated and the CCP4 suite includes several automation pipelines. After giving a brief description of the evolution of CCP4 over the last 30 years, an overview of the current suite is given. While detailed descriptions are given in the accompanying articles, here it is shown how the individual programs contribute to a complete software package.

引用

页码：235 / 242

页数：8

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