Target practice

被引：19

作者：

Sali, A ^{[1
]}

机构：

[1] Rockefeller Univ, Pels Family Ctr Biochem & Struct Biol, Lab Mol Biophys, New York, NY 10021 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2001年 / 8卷 / 06期

关键词：

D O I：

10.1038/88529

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The scope of structural genomics has recently been estimated by simulation of several target selection strategies based on the currently known protein sequence families. Useful characterization of most protein sequences will be possible by protein structure modeling, if structures of -16,000 carefully selected protein domains are determined experimentally. In the absence of globally coordinated target selection, three times as many structures may be required.

引用

页码：482 / 484

页数：3

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