DNA methylation learns to fly

被引：67

作者：

Lyko, F ^{[1
]}

机构：

[1] Deutsch Krebsforschungszentrum, D-69120 Heidelberg, Germany

来源：

TRENDS IN GENETICS | 2001年 / 17卷 / 04期

关键词：

D O I：

10.1016/S0168-9525(01)02234-X

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

For a long time, the fruit fly (Drosophila melanogaster) was considered the archetypal organism that lives well without DNA methylation. However, two recent reports demonstrate the presence of 5-methylcytosine in the Drosophila genome. This apparently contradicts numerous previous experiments that failed to detect methylated DNA. However, it is a particular combination of developmental specificity and unusual target sequences that made DNA methylation in Drosophila so elusive.

引用

页码：169 / 172

页数：4

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