Emergence, mechanism, and clinical implications of reduced glycopeptide susceptibility in Staphylococcus aureus

被引：38

作者：

Geisel, R

Schmitz, FJ

Fluit, AC

Labischinski, H

机构：

[1] Univ Dusseldorf, Inst Med Mikrobiol & Virol, D-40225 Dusseldorf, Germany

[2] Univ Utrecht, Med Ctr, Inst Med Microbiol, Utrecht, Netherlands

[3] Bayer AG, PH Res Antiinfect, D-5600 Wuppertal, Germany

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2001年 / 20卷 / 10期

关键词：

D O I：

10.1007/s100960100595

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In order to understand the mechanism(s) of the resistance/reduced susceptibility of Staphylococcus aureus to glycopeptide antibiotics, the current data on the modes of action of glycopeptides were reviewed. In addition, the different test systems for detecting vancomycin resistance and the clinical relevance of resistant Staphylococcus aureus were analyzed. Finally, strategies to prevent the nosocomial spread of these bacteria are presented, as are new therapeutic options.

引用

收藏

页码：685 / 697

页数：13

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