Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

被引：214

作者：

Donadio, Stefano ^{[1
]}

Monciardini, Paolo ^{[1
]}

Sosio, Margherita ^{[1
]}

机构：

[1] KtedoGen, I-20132 Milan, Italy

来源：

NATURAL PRODUCT REPORTS | 2007年 / 24卷 / 05期

关键词：

D O I：

10.1039/b514050c

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A total of 223 complete bacterial genomes are analyzed, with 281 citations, for the presence of genes encoding modular polyketide synthases (PKS) and nonribosomal peptide synthetases (NRPS). We report on the distribution of these systems in different bacterial taxa and, whenever known, the metabolites they synthesize. We also highlight, in the different bacterial lineages, the PKS and NRPS genes and, whenever known, the corresponding products.

引用

页码：1073 / 1109

页数：37

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