Directed evolution of single proteins, metabolic pathways, and viruses

被引：57

作者：

Schmidt-Dannert, C ^{[1
]}

机构：

[1] Univ Minnesota, Dept Biochem Mol Biol & Biophys, St Paul, MN 55126 USA

来源：

BIOCHEMISTRY | 2001年 / 40卷 / 44期

关键词：

D O I：

10.1021/bi011310c

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：13125 / 13136

页数：12

共 136 条

[11] Yeast surface display for directed evolution of protein expression, affinity, and stability [J].

Boder, ET ;

Wittrup, KD .

APPLICATIONS OF CHIMERIC GENES AND HYBRID PROTEINS, PT C: PROTEIN-PROTEIN INTERACTIONS AND GENOMICS, 2000, 328 :430-444

[12] Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity [J].

Boder, ET ;

Midelfort, KS ;

Wittrup, KD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (20) :10701-10705

[13] A hierarchical approach to protein molecular evolution [J].

Bogarad, LD ;

Deem, MW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (06) :2591-2595

[14] Directed evolution of an esterase: Screening of enzyme libraries based on pH-Indicators and a growth assay [J].

Bornscheuer, UT ;

Altenbuchner, J ;

Meyer, HH .

BIOORGANIC & MEDICINAL CHEMISTRY, 1999, 7 (10) :2169-2173

[15] Evolution of a cytokine using DNA family shuffling [J].

Chang, CCJ ;

Chen, TT ;

Cox, BW ;

Dawes, GN ;

Stemmer, WPC ;

Punnonen, J ;

Patten, PA .

NATURE BIOTECHNOLOGY, 1999, 17 (08) :793-797

[16] Isolation of high-affinity ligand-binding proteins by periplasmic expression with cytometric screening (PECS) [J].

Chen, G ;

Hayhurst, A ;

Thomas, JG ;

Harvey, BR ;

Iverson, BL ;

Georgiou, G .

NATURE BIOTECHNOLOGY, 2001, 19 (06) :537-542

[17] TUNING THE ACTIVITY OF AN ENZYME FOR UNUSUAL ENVIRONMENTS - SEQUENTIAL RANDOM MUTAGENESIS OF SUBTILISIN-E FOR CATALYSIS IN DIMETHYLFORMAMIDE [J].

CHEN, KQ ;

ARNOLD, FH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (12) :5618-5622

[18] Directed evolution of a fungal peroxidase [J].

Cherry, JR ;

Lamsa, MH ;

Schneider, P ;

Vind, J ;

Svendsen, A ;

Jones, A ;

Pedersen, AH .

NATURE BIOTECHNOLOGY, 1999, 17 (04) :379-384

[19] Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria [J].

Christians, FC ;

Loeb, LA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (12) :6124-6128

[20] Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling [J].

Christians, FC ;

Scapozza, L ;

Crameri, A ;

Folkers, G ;

Stemmer, WPC .

NATURE BIOTECHNOLOGY, 1999, 17 (03) :259-264

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