Development of a new platform for neglected tropical disease surveillance

被引:70
作者
Lammie, Patrick J. [1 ]
Moss, Delynn M. [2 ]
Goodhew, E. Brook [1 ]
Hamlin, Katy [1 ]
Krolewiecki, Alejandro [3 ]
West, Sheila K. [4 ]
Priest, Jeffrey W. [2 ]
机构
[1] Ctr Dis Control & Prevent, Div Parasit Dis & Malaria, Atlanta, GA USA
[2] Ctr Dis Control & Prevent, Div Foodborne Waterborne & Environm Dis, Atlanta, GA USA
[3] Univ Nacl Salta, Inst Invest Enfermedades Trop, San Ramon Nueva Oran, Argentina
[4] Johns Hopkins Univ, Wilmer Eye Inst, Dana Ctr Prevent Ophthalmol, Baltimore, MD 21218 USA
基金
比尔及梅琳达.盖茨基金会;
关键词
Multiplex; Neglected tropical disease; Antibody; Elimination; Surveillance; IMMUNOGLOBULIN-G ANTIBODIES; ENTEROTOXIGENIC ESCHERICHIA-COLI; LYMPHATIC FILARIASIS; MULTIPLEX ASSAY; RANDOMIZED-TRIAL; MASS TREATMENT; SERUM SAMPLES; CHILDREN; ANTIGEN; AZITHROMYCIN;
D O I
10.1016/j.ijpara.2012.07.002
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
An expanded global focus on the control and elimination of neglected tropical diseases (NTDs) has called attention to the need to develop and validate surveillance strategies that are cost effective and can be integrated across diseases. Here, we describe a multiplex tool for the sensitive detection of antibody responses to NTDs as well as vaccine preventable diseases, malaria, and waterborne and zoonotic infections. The assay platform is robust, can be performed with either serum or dried blood spots and can be adapted to local epidemiological conditions and public health priorities. Multiplex assays open the door to conducting routine serosurveillance for NTDs through demographic health surveillance or malaria indicator surveys. Published by Elsevier Ltd. on behalf of Australian Society for Parasitology Inc.
引用
收藏
页码:797 / 800
页数:4
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