Minimizing acquisition time of arterial spin labeling at 3T

被引:62
作者
Fernandez-Seara, Maria A. [1 ]
Edlow, Brian L. [2 ]
Hoang, Angela [2 ]
Wang, Jiongjiong [2 ,3 ]
Feinberg, David A. [4 ]
Detre, John A. [2 ,3 ]
机构
[1] Univ Navarra, Ctr Appl Med Res, Neuroimaging Lab, Pamplona 31008, Spain
[2] Univ Penn, Med Ctr, Dept Neurol, Ctr Funct Neuroimaging, Philadelphia, PA 19104 USA
[3] Univ Penn, Med Ctr, Dept Radiol, Philadelphia, PA 19104 USA
[4] Adv MRI Technol, Sebastopol, CA USA
关键词
MRI; perfusion; arterial spin labeling; 3D GRASE; stroke imaging;
D O I
10.1002/mrm.21633
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
An improved arterial spin labeling (ASL) perfusion technique that combines pseudo-continuous labeling and a T-2*-insensitive sequence (GRASE) with background suppression was used to acquire perfusion maps in normal volunteers and stroke patients. It is shown that perfusion measurements obtained in less than 1 min of scan time are reproducible, with a coefficient of variation of 7%. The perfusion maps generated from these data can be used to characterize the stroke lesion.
引用
收藏
页码:1467 / 1471
页数:5
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