Asymmetric cyclopropanation in protic media conducted by chiral bis(hydroxymethyl-dihydrooxazolyl)pyridine-ruthenium catalysts

被引：53

作者：

Iwasa, S ^{[1
]}

Takezawa, F ^{[1
]}

Tuchiya, Y ^{[1
]}

Nishiyama, H ^{[1
]}

机构：

[1] Toyohashi Univ Technol, Sch Mat Sci, Toyohashi, Aichi 4418580, Japan

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 01期

关键词：

D O I：

10.1039/b008516m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cyclopropanation of styrene with diazoacetates, performed in aqueous/organic biphasic media or homogeneous alcoholic media in the combination of toluene by using chiral bis(hydroxymethyldihydrooxazolyl)pyridine-ruthenium catalyst, resulted in high enantiomeric excess up to 96-97% and trans:cis stereoselectivity to 97:3.

引用

页码：59 / 60

页数：2

共 21 条

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