Predicting Vaccine Responsiveness

被引：20

作者：

Boyd, Scott D. ^{[1
]}

Jackson, Katherine J. L. ^{[1
]}

机构：

[1] Stanford Univ, Dept Pathol, Stanford, CA 94305 USA

来源：

CELL HOST & MICROBE | 2015年 / 17卷 / 03期

关键词：

HUMAN MONOCLONAL-ANTIBODIES; YELLOW-FEVER VACCINE; SEASONAL INFLUENZA; SYSTEMS BIOLOGY; B-CELLS; RESPONSES; ANTIGEN; VIRUS; IMMUNOGENICITY; IDENTIFICATION;

D O I：

10.1016/j.chom.2015.02.015

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Vaccination has saved many lives and prevented needless suffering from disease, but it is not always effective. Immune responses are a highly "personalized" aspect of an individual's biology, as they are subject to germline genetic influences but are embodied in cell populations that continuously sample the environment. Additionally, immunity is shaped by memory of prior infectious diseases and other antigenic exposures. Here, we review examples of recent technical advances and insights into human vaccine responses that are helping to define the features associated with successful vaccination and that may enable a more predictive vaccinology in the future. © 2015 Elsevier Inc.

引用

页码：301 / 307

页数：7

共 39 条

[1] Deconstructing the Peptide-MHC Specificity of T Cell Recognition [J].

Birnbaum, Michael E. ;

Mendoza, Juan L. ;

Sethi, Dhruv K. ;

Dong, Shen ;

Glanville, Jacob ;

Dobbins, Jessica ;

Oezkan, Engin ;

Davis, Mark M. ;

Wucherpfennig, Kai W. ;

Garcia, K. Christopher .

CELL, 2014, 157 (05) :1073-1087

[2] Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences [J].

Brodin, Petter ;

Jojic, Vladimir ;

Gao, Tianxiang ;

Bhattacharya, Sanchita ;

Angel, Cesar J. Lopez ;

Furman, David ;

Shen-Orr, Shai ;

Dekker, Cornelia L. ;

Swan, Gary E. ;

Butte, Atul J. ;

Maecker, Holden T. ;

Davis, Mark M. .

CELL, 2015, 160 (1-2) :37-47

[3] Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine [J].

Chen, Jie ;

Liang, Zhenglun ;

Lu, Fengmin ;

Fang, Xin ;

Liu, Shuang ;

Zeng, Ying ;

Zhu, Fengcai ;

Chen, Xiangmei ;

Shen, Tao ;

Li, Jie ;

Zhuang, Hui .

VACCINE, 2011, 29 (04) :706-711

[4] Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine [J].

Corti, Davide ;

Suguitan, Amorsolo L., Jr. ;

Pinna, Debora ;

Silacci, Chiara ;

Fernandez-Rodriguez, Blanca M. ;

Vanzetta, Fabrizia ;

Santos, Celia ;

Luke, Catherine J. ;

Torres-Velez, Fernando J. ;

Temperton, Nigel J. ;

Weiss, Robin A. ;

Sallusto, Federica ;

Subbarao, Kanta ;

Lanzavecchia, Antonio .

JOURNAL OF CLINICAL INVESTIGATION, 2010, 120 (05) :1663-1673

[5] In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire [J].

DeKosky, Brandon J. ;

Kojima, Takaaki ;

Rodin, Alexa ;

Charab, Wissam ;

Ippolito, Gregory C. ;

Ellington, Andrew D. ;

Georgiou, George .

NATURE MEDICINE, 2015, 21 (01) :86-91

[6] High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire [J].

DeKosky, Brandon J. ;

Ippolito, Gregory C. ;

Deschner, Ryan P. ;

Lavinder, Jason J. ;

Wine, Yariv ;

Rawlings, Brandon M. ;

Varadarajan, Navin ;

Giesecke, Claudia ;

Doerner, Thomas ;

Andrews, Sarah F. ;

Wilson, Patrick C. ;

Hunicke-Smith, Scott P. ;

Willson, C. Grant ;

Ellington, Andrew D. ;

Georgiou, George .

NATURE BIOTECHNOLOGY, 2013, 31 (02) :166-169

[7] Variations in measles vaccine-specific humoral immunity by polymorphisms in SLAM and CD46 measles virus receptors [J].

Dhiman, Neelam ;

Poland, Gregory A. ;

Cunningham, Julie M. ;

Jacobson, Robert M. ;

Ovsyannikova, Inna G. ;

Vierkant, Robert A. ;

Wu, Yanhong ;

Pankratz, V. Shane .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 120 (03) :666-672

[8] Antibody landscapes after influenza virus infection or vaccination [J].

Fonville, J. M. ;

Wilks, S. H. ;

James, S. L. ;

Fox, A. ;

Ventresca, M. ;

Aban, M. ;

Xue, L. ;

Jones, T. C. ;

Le, N. M. H. ;

Pham, Q. T. ;

Tran, N. D. ;

Wong, Y. ;

Mosterin, A. ;

Katzelnick, L. C. ;

Labonte, D. ;

Le, T. T. ;

van der Net, G. ;

Skepner, E. ;

Russell, C. A. ;

Kaplan, T. D. ;

Rimmelzwaan, G. F. ;

Masurel, N. ;

de Jong, J. C. ;

Palache, A. ;

Beyer, W. E. P. ;

Le, Q. M. ;

Nguyen, T. H. ;

Wertheim, H. F. L. ;

Hurt, A. C. ;

Osterhaus, A. D. M. E. ;

Barr, I. G. ;

Fouchier, R. A. M. ;

Horby, P. W. ;

Smith, D. J. .

SCIENCE, 2014, 346 (6212) :996-1000

[9] Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation [J].

Glanville, Jacob ;

Kuo, Tracy C. ;

von Buedingen, H. -Christian ;

Guey, Lin ;

Berka, Jan ;

Sundar, Purnima D. ;

Huerta, Gabriella ;

Mehta, Gautam R. ;

Oksenberg, Jorge R. ;

Hauser, Stephen L. ;

Cox, David R. ;

Rajpal, Arvind ;

Pons, Jaume .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (50) :20066-20071

[10] Linking T-cell receptor sequence to functional phenotype at the single-cell level [J].

Han, Arnold ;

Glanville, Jacob ;

Hansmann, Leo ;

Davis, Mark M. .

NATURE BIOTECHNOLOGY, 2014, 32 (07) :684-+

← 1 2 3 4 →