Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models

被引:177
作者
Todd, JA [1 ]
Wicker, LS [1 ]
机构
[1] Univ Cambridge, Inst Med Res, Wellcome Trust Diabet & Inflammat Lab, Juvenile Diabet Res Fdn, Cambridge CB2 2XY, England
基金
英国惠康基金;
关键词
D O I
10.1016/S1074-7613(01)00202-3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Populations of humans and mice contain alleles at many loci that protect from immune-mediated diseases. Identification of these alleles, some which are likely to function in immune recognition, tolerance, and regulation, will facilitate the development of diagnostics as well as therapeutics that alter disease progression.
引用
收藏
页码:387 / 395
页数:9
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