Toward an improved understanding of the unusual reactivity of pd0/trialkylphosphane catalysts in cross-couplings of alkyl electrophiles:: Quantifying the factors that determine the rate of oxidative addition

被引：153

作者：

Hills, ID ^{[1
]}

Netherton, MR ^{[1
]}

Fu, GC ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 46期

关键词：

cross-coupling; homogeneous catalysis; palladium phosphane; ligands; reaction mechanisms;

D O I：

10.1002/anie.200352858

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

What a difference a ligand makes! The reactivity of Pd 0/trialkylphosphane complexes is of great interest because of their unusual effectiveness as cross-coupling catalysts for alkyl electrophiles [Eq. (1)]. This study sheds light on various aspects of the critical oxidative-addition step of the catalytic cycle.

引用

页码：5749 / 5752

页数：4

共 54 条

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HILLS ID, UNPUB

[22] CHLOROCARBON ACTIVATION - CATALYTIC CARBONYLATION OF DICHLOROMETHANE AND CHLOROBENZENE [J].