Interactions of nitrogen-containing xenobiotics with monoamine oxidase (MAO) isozymes A and B: SAR studies on MAO substrates and inhibitors

被引：174

作者：

Kalgutkar, AS ^{[1
]}

Dalvie, DK

Castagnoli, N

Taylor, TJ

机构：

[1] Pfizer Global Res & Dev, Pharmacokinet Dynam & Metab Dept, Groton, CT 06340 USA

[2] Virginia Polytech Inst & State Univ, Dept Chem, Peters Ctr Study Parkinsons Dis, Blacksburg, VA 24061 USA

来源：

CHEMICAL RESEARCH IN TOXICOLOGY | 2001年 / 14卷 / 09期

关键词：

D O I：

10.1021/tx010073b

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：1139 / 1162

页数：24

共 300 条

[1]

ABELL CW, 1994, HETEROCYCLES, V39, P933

[2] QUANTITATIVE STRUCTURE METABOLISM RELATIONSHIP ANALYSES OF MAO-MEDIATED TOXICATION OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE AND ANALOGS [J].

ALTOMARE, C ;

CARRUPT, PA ;

GAILLARD, P ;

ELTAYAR, N ;

TESTA, B ;

CAROTTI, A .

CHEMICAL RESEARCH IN TOXICOLOGY, 1992, 5 (03) :366-375

[3] Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: Effects of lipophilicity and structure-activity relationships [J].

Altomare, C ;

Cellamare, S ;

Summo, L ;

Catto, M ;

Carotti, A ;

Thull, U ;

Carrupt, PA ;

Testa, B ;

Stoeckli-Evans, H .

JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (20) :3812-3820

[4] Deuterium isotope effect studies on the MAO-B catalyzed oxidation of 4-benzyl-1-cyclopropyl-1,2,3,6-tetrahydropyridine [J].

Anderson, AH ;

Kuttab, S ;

Castagnoli, N .

BIOCHEMISTRY, 1996, 35 (10) :3335-3340

[5] Alkylbenzyl ethers of hydroquinones as monoamine oxidase B inhibitors [J].

Arvanitis, AG ;

Scholfield, EL ;

Grigoriadis, D ;

Heytler, PG ;

Bowdle, J ;

Chorvat, RJ .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1996, 6 (02) :115-120

[6] CDNA CLONING OF HUMAN-LIVER MONOAMINE OXIDASE-A AND OXIDASE-B - MOLECULAR-BASIS OF DIFFERENCES IN ENZYMATIC-PROPERTIES [J].

BACH, AWJ ;

LAN, NC ;

JOHNSON, DL ;

ABELL, CW ;

BEMBENEK, ME ;

KWAN, SW ;

SEEBURG, PH ;

SHIH, JC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (13) :4934-4938

[7]

BARWELL CJ, 1988, B PHARM RES COMMUN, V20, P101

[8] STUDIES OF THE INVITRO OXIDATION OF 1-METHYL-4-(1-METHYLPYRROL-2-YL)-4-PIPERIDINOL AND ITS DEHYDRATION PRODUCT 1,2,3,6-TETRAHYDRO-1-METHYL-4-(METHYLPYRROL-2-YL) PYRIDINE BY HUMAN MONOAMINE OXIDASE-A AND OXIDASE-B [J].

BEMBENEK, ME .

LIFE SCIENCES, 1990, 46 (25) :1873-1877

[9] INHIBITION OF MONOAMINE OXIDASE-A AND MONOAMINE OXIDASE-B BY SIMPLE ISOQUINOLINE ALKALOIDS - RACEMIC AND OPTICALLY-ACTIVE 1,2,3,4-TETRAHYDRO-ISOQUINOLINE, 3,4-DIHYDRO-ISOQUINOLINE, AND FULLY AROMATIC ISOQUINOLINE [J].

BEMBENEK, ME ;

ABELL, CW ;

CHRISEY, LA ;

ROZWADOWSKA, MD ;

GESSNER, W ;

BROSSI, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (01) :147-152

[10]

Benedetti MS, 1998, J NEURAL TRANSM-SUPP, P149

← 1 2 3 4 5 6 7 8 9 10 →