ER biogenesis: Self-assembly of tubular topology by protein hairpins

被引:19
作者
Shnyrova, Anna [1 ]
Frolov, Vadim A. [1 ]
Zimmerberg, Joshua [1 ]
机构
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Program Phys Biol, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1016/j.cub.2008.04.031
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
The structure of the endoplasmic reticulum (ER) depends on members of the reticulon and DP1/Yop1p families. Two of these proteins are sufficient to form tubular membrane networks from pure phospholipid vesicles, thus revealing a new paradigm of ER morphogenesis.
引用
收藏
页码:R474 / R476
页数:3
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