Get a grip:: integrins in cell-biomaterial interactions

被引:243
作者
García, AJ [1 ]
机构
[1] Georgia Inst Technol, Petit Inst Bioengn & Biosci, Woodruff Sch Mech Engn, Atlanta, GA 30332 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
integrins; cell adhesion; extracellular matrix; signaling; inflammation; biomimetic materials; RGD;
D O I
10.1016/j.biomaterials.2005.05.029
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Integrin adhesion receptors have emerged as central regulators of cell-biomaterial interactions. This opinion paper discusses how integrins control cellular and host responses to biornaterials and new strategies to manipulate these adhesive interactions in order to elicit specific cellular responses. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7525 / 7529
页数:5
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