Photoactivatable fluorescent proteins

被引:356
作者
Lukyanov, KA
Chudakov, DM
Lukyanov, S
Verkhusha, VV
机构
[1] Russian Acad Sci, Inst Bioorgan Chem, Moscow 117997, Russia
[2] Univ Colorado, Dept Pharmacol, Aurora, CO 80045 USA
[3] Hlth Sci Ctr, Aurora, CO 80045 USA
关键词
D O I
10.1038/nrm1741
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The fluorescence characteristics of photoactivatable proteins can be controlled by irradiating them with light of a specific wavelength, intensity and duration. This provides unique possibilities for the optical labelling and tracking of living cells, organelles and intracellular molecules in a spatio-temporal manner. Here, we discuss the properties of the available photoactivatable fluorescent proteins and their potential applications.
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页码:885 / 891
页数:7
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