Synthesis of spiro- and fused heterocycles by palladium catalysed carbo- and heteroannulation cascades of allenes

被引：88

作者：

Grigg, R ^{[1
]}

Köppen, I ^{[1
]}

Rasparini, M ^{[1
]}

Sridharan, V ^{[1
]}

机构：

[1] Univ Leeds, Sch Chem, Mol Innovat Divers & Automated Synth Ctr, Leeds LS2 9JT, W Yorkshire, England

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 11期

关键词：

D O I：

10.1039/b102046n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two novel palladium catalysed cascade processes involving the generation of a (pi -allyl)palladium intermediate from allenes in an intra- or intermolecular fashion, followed by regioselective intramolecular nucleophilic addition of amines, alcohols or malonates provide spiro- or linear fused heterocycles in good yield.

引用

页码：964 / 965

页数：2

共 7 条

[1] Palladium-indium mediated Barbier-type allylation of aldehydes with allenes [J].