Novel synthesis of 2-aryl and 2,3-disubstituted Indoles by modified double elimination protocol

被引：19

作者：

Babu, G ^{[1
]}

Orita, A ^{[1
]}

Otera, J ^{[1
]}

机构：

[1] Okayama Univ Sci, Dept Appl Chem, Okayama 7000005, Japan

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 21期

关键词：

D O I：

10.1021/ol051826e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Syntheses of 2-aryl and 2,3-substituted indoles were realized by modified double elimination protocol. Under basic conditions, vinyl sulfones derived from the reaction of 2-aminobenzyl sulfone with benzaldehydes underwent cyclization and alkylation followed by elimination of sulfinic acid to afford 2,3-substituted indoles.

引用

页码：4641 / 4643

页数：3

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