Frequency of the C282Y mutation of hemochromatosis in five French populations

被引：26

作者：

Mercier, G ^{[1
]}

Bathelier, C ^{[1
]}

Lucotte, G ^{[1
]}

机构：

[1] Hop Maison Blanche, Mol Neurogenet Lab, Serv Neurol, F-51092 Reims, France

来源：

BLOOD CELLS MOLECULES AND DISEASES | 1998年 / 24卷 / 09期

关键词：

hereditary hemochromatosis; C282Y mutation; French populations;

D O I：

10.1006/bcmd.1998.0183

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hereditary hemochromatosis mutation 845A (C282Y) in the HFE gene was recently described, and the C282Y frequencies were reported for various world populations. The aim of this study was to determine the Y allele frequencies of the C282Y mutation for five French populations. The most elevated value (=5.6%) was obtained for Bretons, in accordance to the hypothesis indicating a Celtic origin of the hereditary hemochromatosis mutation. (C) 1998 Academic Press.

引用

页码：165 / 166

页数：2