In situ molecular profiling of breast cancer biomarkers with multicolor quantum dots

被引：163

作者：

Yezhelyev, Maksym V.

Al-Hajj, Ahmad

Morris, Caroline

Marcus, Adam I.

Liu, Tonqrui

Lewis, Melinda

Cohen, Cynthia

Zrazhevskiy, Pasha

Simons, Jonathan W.

Rogatko, Andre

Nie, Shuming

Gao, Xiaohu ^{[1
]}

O'Regan, Ruth M.

机构：

[1] Univ Washington, Dept Bioengn, Seattle, WA 98195 USA

[2] Emory Univ, Winship Canc Ctr, Atlanta, GA 30322 USA

[3] Emory Univ, Dept Biomed Engn, Atlanta, GA 30322 USA

来源：

ADVANCED MATERIALS | 2007年 / 19卷 / 20期

关键词：

D O I：

10.1002/adma.200701983

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Quantum dot bioconjugates can be used for multiplexed and quantitative detection of tumor biomarkers in cells and tissues. This new technology should have significant impact on molecular pathology if validated with traditional techniques (such as western blotting, FISH, and IHC), and with large-scale clinical studies. In addition, it could also become the first clinical application of quantum dots.

引用

收藏

页码：3146 / +

页数：7

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