New approaches for imaging tumour responses to treatment

被引：350

作者：

Brindle, Kevin ^{[1
,2
]}

机构：

[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1GA, England

[2] Li Ka Shing Ctr, Cambridge Res Inst, Cambridge CB2 ORE, England

来源：

NATURE REVIEWS CANCER | 2008年 / 8卷 / 02期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1038/nrc2289

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Tumour responses to treatment are still largely assessed from imaging measurements of reductions in tumour size. However, this can take several weeks to become manifest and in some cases may not occur at all, despite a positive response to treatment. There has been considerable interest, therefore, in non-invasive techniques for imaging tissue function that can give early evidence of response. These can be used in clinical trials of new drugs to give an early indication of drug efficacy, and subsequently in the clinic to select the most effective therapy at an early stage of treatment.

引用

页码：94 / 107

页数：14

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