Preparation of tris-based dendrimer-grafted core-shell type resin for solid-phase peptide synthesis

被引：14

作者：

Cho, JK ^{[1
]}

Kim, DW ^{[1
]}

Namgung, J ^{[1
]}

Lee, YS ^{[1
]}

机构：

[1] Seoul Natl Univ, Sch Chem Engn, Seoul 151742, South Korea

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 42期

关键词：

D O I：

10.1016/S0040-4039(01)01560-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel symmetrical dendrimer monomer was synthesized from tris(hydroxymethyl)aminomethane (Tris) and repeatedly Coupled to a core-shell type resin. The loading capacity, of amino groups was increased up to 4.0 mmol g(1) resin by the dendrimerization process. The high loading dendrimer-grafted resin produced was successfully applied to solid-phase peptide synthesis (SPPS). (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：7443 / 7445

页数：3

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