Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties

被引：55

作者：

Barbayianni, E

Fotakopoulou, I

Schmidt, M

Constantinou-Kokotou, V

Bornscheuer, UT

Kokotos, G

机构：

[1] Univ Athens, Dept Chem, Organ Chem Lab, GR-15771 Athens, Greece

[2] Agr Univ Athens, Chem Labs, Athens 11855, Greece

[3] Ernst Moritz Arndt Univ Greifswald, Inst Chem & Biochem, Dept Tech Chem & Biotechnol, D-17487 Greifswald, Germany

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 22期

关键词：

D O I：

10.1021/jo051004v

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Enzymes are versatile reagents for the efficient removal of methyl and benzyl protecting groups. An esterase from Bacillus subtilis (BS2) and a lipase from Candida antarctica (CAL-A) allow a mild and selective removal of these moieties in high yields without affecting other functional groups.

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收藏

页码：8730 / 8733

页数：4

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