Direct vascular effects of estrogens and selective estrogen receptor modulators

被引:40
作者
Simoncini, T [1 ]
Genazzani, AR [1 ]
机构
[1] Univ Pisa, Dept Reprod Med & Child Dev, Div Obstet & Gynecol, I-56100 Pisa, Italy
关键词
D O I
10.1097/00001703-200006000-00004
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The aim of this review is to provide an update on the latest advancements in the field of the action of estrogens on the cardiovascular system, and particularly on the molecular mechanisms of the direct effects of these hormones and of some of the new synthetic selective estrogen receptor modulators on the vascular wall, (C) 2000 Lippincott Williams & Wilkins.
引用
收藏
页码:181 / 187
页数:7
相关论文
共 74 条
  • [31] Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women
    Hulley, S
    Grady, D
    Bush, T
    Furberg, C
    Herrington, D
    Riggs, B
    Vittinghoff, E
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (07): : 605 - 613
  • [32] Estrogen inhibits the vascular injury response in estrogen receptor alpha-deficient mice
    Iafrati, MD
    Karas, RH
    Aronovitz, M
    Kim, S
    Sullivan, TR
    Lubahn, DB
    ODonnell, TF
    Korach, KS
    Mendelsohn, ME
    [J]. NATURE MEDICINE, 1997, 3 (05) : 545 - 548
  • [33] Estrogen upregulates cyclooxygenase-1 gene expression in ovine fetal pulmonary artery endothelium
    Jun, SS
    Chen, Z
    Pace, MC
    Shaul, PW
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (01) : 176 - 183
  • [34] Estrogen inhibits the vascular injury response in estrogen receptor β-deficient female mice
    Karas, RH
    Hodgin, JB
    Kwoun, M
    Krege, JH
    Aronovitz, M
    Mackey, W
    Gustafsson, JÅ
    Korach, KS
    Smithies, O
    Mendelsohn, ME
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (26) : 15133 - 15136
  • [35] HUMAN VASCULAR SMOOTH-MUSCLE CELLS CONTAIN FUNCTIONAL ESTROGEN-RECEPTOR
    KARAS, RH
    PATTERSON, BL
    MENDELSOHN, ME
    [J]. CIRCULATION, 1994, 89 (05) : 1943 - 1950
  • [36] Estrogens increase transcription of the human endothelial NO synthase gene -: Analysis of the transcription factors involved
    Kleinert, H
    Wallerath, T
    Euchenhofer, C
    Ihrig-Biedert, I
    Li, H
    Förstermann, U
    [J]. HYPERTENSION, 1998, 31 (02) : 582 - 588
  • [37] Vascular effects of estrogen and vitamin E therapies in postmenopausal women
    Koh, KK
    Blum, A
    Hathaway, L
    Mincemoyer, R
    Csako, G
    Waclawiw, MA
    Panza, JA
    Cannon, RO
    [J]. CIRCULATION, 1999, 100 (18) : 1851 - 1857
  • [38] Effects of hormone therapy on inflammatory cell adhesion molecules in postmenopausal healthy women
    Koh, KK
    Bui, MN
    Mincemoyer, R
    Cannon, RO
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1997, 80 (11) : 1505 - 1507
  • [39] Krasinski K, 1997, CIRCULATION, V95, P1768
  • [40] Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium
    LantinHermoso, RL
    Rosenfeld, CR
    Yuhanna, IS
    German, Z
    Chen, Z
    Shaul, PW
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 1997, 273 (01) : L119 - L126