Magic angle spinning NMR: A valuable tool for monitoring the progress of reactions in solid phase synthesis

被引：59

作者：

Wehler, T

Westman, J

机构：

[1] Structural Chemistry, Pharmacia and Upjohn

[2] Medicinal Chemistry, Pharmacia and Upjohn

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 27期

关键词：

D O I：

10.1016/0040-4039(96)00931-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Proton NMR-spectra of four different solid supports were obtained using the magic angle spinning Nano NMR probe to evaluate their utility in solid phase chemistry. It was possible to analyse the spectra in respect to structure and quantity. An intramolecular cyclisation reaction on the solid support in the Nano tube could be followed directly. Copyright (C) 1996 Elsevier Science Ltd

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页码：4771 / 4774

页数：4

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