Fragile X syndrome with anxiety disorder and exceptional verbal intelligence

被引：9

作者：

Angkustsiri, Kathleen ^{[1
,2
]}

Wirojanan, Juthamas ^{[1
,3
]}

Deprey, Lesley J. ^{[1
]}

Gane, Louise W. ^{[1
]}

Hagerman, Randi J. ^{[1
,2
]}

机构：

[1] Univ Calif Davis, MIND Inst, Med Ctr, Sacramento, CA 95817 USA

[2] Univ Calif Davis, Med Ctr, Dept Pediat, Sacramento, CA 95817 USA

[3] Prince Songkla Univ, Fac Med, Dept Pediat, Hat Yai, Songkhla, Thailand

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS PART A | 2008年 / 146A卷 / 03期

关键词：

fragile X syndrome; anxiety disorder; verbal intelligence;

D O I：

10.1002/ajmg.a.32118

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Fragile X syndrome (FXS) is often characterized by mental retardation. However, FXS is also associated with significant emotional and psychiatric problems, including anxiety, depression, attention difficulties, and learning disabilities in the presence of a normal IQ. This report describes a unique woman with the full mutation of FXS who has an exceptional profile of above-average intelligence combined with significant impairments due to anxiety and learning disability. Women with FXS can present primarily with learning and emotional problems, and clinicians should consider FXS in these women regardless of their IQ. (C) 2008 Wiley-Liss, Inc.

引用

页码：376 / 379

页数：4

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