The role of prechordal mesendoderm in neural patterning

被引：69

作者：

Kiecker, C ^{[1
]}

Niehrs, C ^{[1
]}

机构：

[1] Deutsch Krebsforschungszentrum, Div Mol Embryol, D-69120 Heidelberg, Germany

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2001年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0959-4388(00)00170-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Prechordal mesendoderm is formed in response to Nodal and maternal beta -Catenin signaling and is regulated by signals from anterior endoderm and chordamesoderm. Prechordal mesendodermal cells are involved in neural induction and in anteroposterior and dorsoventral neural patterning. Inhibitors of Wnt and BMP growth factors secreted by prechordal mesendoderm mediate neural induction and anteroposterior and dorsoventral patterning, whereas SHH and TGF betas mediate dorsoventral patterning.

引用

页码：27 / 33

页数：7

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