Mast cell proliferative disorders: current view on variants recognized by the World Health Organization

被引：56

作者：

Valent, P

Akin, C

Sperr, WR

Horny, HP

Metcalfe, DD

机构：

[1] Univ Vienna, Dept Internal Med 1, Div Hematol & Hemostaseol, Vienna, Austria

[2] NIH, Lab Allerg Dis, Bethesda, MD 20892 USA

[3] Med Univ Lubeck, Inst Pathol, D-23538 Lubeck, Germany

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2003年 / 17卷 / 05期

关键词：

D O I：

10.1016/S0889-8588(03)00089-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mastocytosis is a heterogeneous group of disorders characterized by abnormal growth and accumulation of mast cells in one or more organs. Systemic variants of disease can be regarded as myeloproliferative disorders. Similar to other myeloid neoplasms, systemic mastocytosis shows a variable clinical course and prognosis and can progress into frank leukemia. The treatment of mastocytosis must be adjusted to the individual situation in each patient and the subtype of disease.

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页码：1227 / +

页数：16

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