Pathogenicity of a ratite-origin influenza A H5 virus in ostriches (Struthio, camelus)

被引：13

作者：

Clavijo, A ^{[1
]}

Riva, J ^{[1
]}

Pasick, J ^{[1
]}

机构：

[1] Natl Ctr Foreign Anim Dis, Winnipeg, MB R3E 3M4, Canada

来源：

AVIAN DISEASES | 2003年 / 47卷

关键词：

avian influenza; orthomyxovirus; ostrich; pathogenicity;

D O I：

10.1637/0005-2086-47.s3.1203

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Ostriches were inoculated with a highly pathogenic avian influenza (HPAI) virus of ratite origin, A/emu/Texas/39924/93 (H5N2) clone clB. The aim of this study was to evaluate the pathogenicity of this isolate for ostriches and to assess the ability of routine virologic and serologic tests to detect infection. Avian influenza virus (AIV) was isolated from tracheal swabs from 2 to 12 days postinfection and from cloacal swabs from 3 to 10 days postinfection. AIV was also isolated from a wide range of tissues. Birds seroconverted as early as 7 days postinfection. This study indicates that HPAI virus of ratite origin replicates extensively in infected ostriches without causing significant clinical disease or mortality.

引用

页码：1203 / 1207

页数：5

共 8 条

[1] ISOLATION OF AN INFLUENZA-A VIRUS FROM OSTRICHES (STRUTHIO-CAMELUS) [J].

ALLWRIGHT, DM ;

BURGER, WP ;

GEYER, A ;

TERBLANCHE, AW .

AVIAN PATHOLOGY, 1993, 22 (01) :59-65

[2]

[Anonymous], IMMUNOLOGY

[3] Experimental infection of emus (Dromaiius novaehollandiae) with avian influenza viruses of varying virulence:: clinical signs, virus shedding and serology [J].

Heckert, RA ;

McIsacc, M ;

Chan, M ;

Zhou, EM .

AVIAN PATHOLOGY, 1999, 28 (01) :13-16

[4] Isolation of influenza A virus, subtype H5N2, and avian paramyxovirus type 1 from a flock of ostriches in Europe [J].

Jorgensen, PH ;

Nielsen, OL ;

Hansen, C ;

Manvell, RJ ;

Banks, J ;

Alexander, DJ .

AVIAN PATHOLOGY, 1998, 27 (01) :15-20

[5] PRESENCE OF AVIAN INFLUENZA-VIRUS (AIV) SUBTYPES H5N2 AND H7N1 IN EMUS (DROMAIUS-NOVAEHOLLANDIAE) AND RHEAS (RHEA-AMERICANA) - VIRUS ISOLATION AND SEROLOGIC FINDINGS [J].

PANIGRAHY, B ;

SENNE, DA ;

PEARSON, JE .

AVIAN DISEASES, 1995, 39 (01) :64-67

[6] An Arg-Lys insertion at the hemagglutinin cleavage site of an H5N2 avian influenza isolate [J].

Perdue, ML ;

Garcia, M ;

Beck, J ;

Brugh, M ;

Swayne, DE .

VIRUS GENES, 1996, 12 (01) :77-84

[7] Assessment of the ability of ratite-origin influenza viruses to infect and produce disease in rheas and chickens [J].

Swayne, DE ;

Beck, JR ;

Perdue, ML ;

Brugh, M ;

Slemons, RD .

AVIAN DISEASES, 1996, 40 (02) :438-447

[8] Evaluation of antibody responses of emus (Dromaius novaehollandiae) to avian influenza virus infection [J].

Zhou, EM ;

Chan, M ;

McIsaac, M ;

Heckert, RA .

AVIAN DISEASES, 1998, 42 (04) :757-761

← 1 →