Adverse reactions to nonsteroidal anti-inflammatory drugs

被引：27

作者：

Stevenson, DD ^{[1
]}

机构：

[1] Scripps Clinic, Div Allergy Asthma & Immunol, Dept Med, La Jolla, CA 92037 USA

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 1998年 / 18卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0889-8561(05)70038-2

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) induce several adverse side effects. Some are caused by the shared pharmacologic effects of all NSAIDs in inhibiting a ubiquitous enzyme, cyclo-oxygenase. Other reactions are idiosyncratic or drug-specific and include hepatitis, erythema multiforme, and multiple blood dyscrasias. In addition, several pseudo-allergic and allergic adverse reactions to aspirin and other NSAIDs have been recognized. This article reviews these diverse reactions to aspirin and NSAIDs in detail. In addition, current investigations of alleged adverse effects and cross-reactivity of food additives and dyes also are reviewed.

引用

页码：773 / +

页数：27

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