Using Small Molecules to Prepare Vesicles with Designable Shapes and Sizes via Frame-Guided Assembly Strategy

被引：31

作者：

Dong, Yuanchen ^{[1
]}

Yang, Zhongqiang ^{[1
]}

Liu, Dongsheng ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China

来源：

SMALL | 2015年 / 11卷 / 31期

基金：

中国国家自然科学基金;

关键词：

amphiphiles; frame guided assembly; leading hydrophobic groups; small molecule; vesicles; MODEL; HYBRIDIZATION; GEOMETRY;

D O I：

10.1002/smll.201500240

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Following the principle of frame-guided assembly (FGA), a small amphiphilic molecule, sodium dodecyl sulfate, is shown to form vesicles with cholesterol as the leading hydrophobic group. These findings not only demonstrate the generality of the FGA but also provide a clue to understand the formation mechanism of the cell membrane, and even the origin of life. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

收藏

页码：3768 / 3771

页数：4

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