Frame-Guided Assembly of Vesicles with Programmed Geometry and Dimensions

被引:96
作者
Dong, Yuanchen [1 ]
Sun, Yawei [1 ]
Wang, Liying [2 ,3 ]
Wang, Dianming [1 ]
Zhou, Tao [1 ]
Yang, Zhongqiang [1 ]
Chen, Zhong [4 ,5 ]
Wang, Qiangbin [4 ,5 ]
Fan, Qinghua [2 ,3 ]
Liu, Dongsheng [1 ]
机构
[1] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China
[2] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100864, Peoples R China
[3] Chinese Acad Sci, Grad Sch, Beijing 100864, Peoples R China
[4] Chinese Acad Sci, Div Nanobiomed, Beijing 100864, Peoples R China
[5] Chinese Acad Sci, i Lab, Suzhou Inst Nanotech & Nanobion, Beijing 100864, Peoples R China
基金
中国国家自然科学基金;
关键词
frame-guided assembly; leading hydrophobic groups; self-assembly; vesicles; GOLD NANOPARTICLES; BLOCK-COPOLYMERS; DNA; DENDRIMERS; SURFACES; FILMS;
D O I
10.1002/anie.201310715
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In molecular self-assembly molecules form organized structures or patterns. The control of the self-assembly process is an important and challenging topic. Inspired by the cytoskeletal-membrane protein lipid bilayer system that determines the shape of eukaryotic cells, we developed a frame-guided assembly process as a general strategy to prepare heterovesicles with programmed geometry and dimensions. This method offers greater control over self-assembly which may benefit the understanding of the formation mechanism as well as the functions of the cell membrane.
引用
收藏
页码:2607 / 2610
页数:4
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