Chromatin boundaries: Punctuating the genome

被引：37

作者：

Kellum, R

Elgin, SCR

机构：

[1] McGill Univ, Dept Biol, Montreal, PQ H3A 1B1, Canada

[2] Washington Univ, Dept Biol, St Louis, MO 63130 USA

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 15期

关键词：

D O I：

10.1016/S0960-9822(07)00337-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transcriptional enhancers are constrained to act within domains defined by boundary elements. How these elements work is a mystery. A recent study emphasizes their autonomous activity; another emphasizes their dependence on nuclear organization. Both effects need to be accounted for by any successful model.

引用

收藏

页码：R521 / R524

页数：4

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