Redox redux: Revisiting PTPs and the control of cell signaling

被引：595

作者：

Tonks, NK ^{[1
]}

机构：

[1] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA

来源：

CELL | 2005年 / 121卷 / 05期

关键词：

D O I：

10.1016/j.cell.2005.05.016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The architecture of the active site of members of the protein tyrosine phosphatase (PTP) superfamily renders these enzymes sensitive to reversible oxidation and inactivation. The importance of reversible oxidation of PTP superfamily members in controlling the signal output following an extracellular stimulus is discussed.

引用

页码：667 / 670

页数：4

共 17 条

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