Electroactive nanoarrays for biospecific ligand mediated studies of cell adhesion

被引：37

作者：

Hoover, Diana K. ^{[1
]}

Lee, Eun-Ju ^{[1
]}

Chan, Eugene W. L. ^{[1
]}

Yousaf, Muhammad N. ^{[1
]}

机构：

[1] Univ N Carolina, Carolina Ctr Genome Sci, Dept Chem, Chapel Hill, NC 27599 USA

来源：

CHEMBIOCHEM | 2007年 / 8卷 / 16期

关键词：

DIP-PEN NANOLITHOGRAPHY; PROTEIN NANOARRAYS; NANOSTRUCTURES; IMMOBILIZATION; DENSITY;

D O I：

10.1002/cbic.200700421

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dip-pen nanolithography was used to form arrays of nanometer-sized spots of an electroactive hydroquinone-terminated alkanethiol on gold substrates. Two different affinity adhesive ligands, linear Arg-Gly-Asp (RGD) and cyclic RGD, were immobilized by this method, and the effects of ligand affinity on the focal adhesions within the fibroblast cells were compared and analyzed.

引用

页码：1920 / +

页数：5

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