The antitumor effect of locoregional magnetic cobalt ferrite in dog mammary adenocarcinoma

被引：35

作者：

Sincai, M

Gânga, D

Bica, D

Vékás, L

机构：

[1] Fac Vet Med, Dept Histol & Cell Biol, Timisoara 1900, Romania

[2] Romanian Acad, Timisoara Branch, Ctr Fundamental & Adv Tech Res, Lab Magnet Fluids, Timisoara, Romania

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2001年 / 225卷 / 1-2期

关键词：

antitumor effect; cobalt ferrite; mammary tumor; adenocarcinoma; dog; breast tumor; magnetic cobalt particles; endocytosis;

D O I：

10.1016/S0304-8853(00)01263-4

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The endocytosis of nanosized magnetic particles by tumor cells led to numerous tests to establish the use of this phenomenon in antitumor therapy. The direct antitumor effect of a biocompatible cobalt-ferrite-based magnetic fluid directly inoculated in bitch mammary tumors was studied. A direct correlation between tumor cell lysis and cobalt ferrite was established in tumors. Massive endocytosis of magnetic particles was observed 1 h after the contact of magnetic fluid with tumor cells. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：235 / 240

页数：6