Molecular diagnostics in medical microbiology: yesterday, today and tomorrow

被引：31

作者：

van Belkum, A ^{[1
]}

机构：

[1] Erasmus MC, Dept Med Microbiol & Infect Dis, Unit Res & Dev, NL-3015 GD Rotterdam, Netherlands

来源：

CURRENT OPINION IN PHARMACOLOGY | 2003年 / 3卷 / 05期

关键词：

D O I：

10.1016/S1471-4892(03)00108-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Clinical microbiology is clearly on the move, and various new diagnostic technologies have been introduced into laboratory practice over the past few decades. However, Henri D Isenberg recently stated that molecular biology techniques promised to revolutionise the diagnosis of infectious disease, but that, to date, this promise is still in its infancy. Molecular diagnostics have now surpassed these early stages and have definitely reached puberty. Currently, a second generation of automated molecular approaches is already within the microbiologists' reach. Quantitative amplification tests in combination with genomics, transcriptomics, proteomics and related methodologies will pave the way to further enhancement of innovative microbial detection and identification.

引用

页码：497 / 501

页数：5

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