Antimicrobial susceptibilities of unique Stenotrophomonas maltophilia clinical strains

被引：72

作者：

Valdezate, S

Vindel, A

Loza, E

Baquero, F

Cantón, R

机构：

[1] Hosp Ramon & Cajal, Microbiol Serv, E-28034 Madrid, Spain

[2] Inst Salud Carlos III, Ctr Nacl Microbiol, Lab Infecc Intrahosp, Madrid 28220, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 05期

关键词：

D O I：

10.1128/AAC.45.5.1581-1584.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Susceptibility to 41 antimicrobials was studied with 99 Stenotrophomonas maltophilia strains, and different pulsed-field gel electrophoresis profiles were identified among 130 prospectively collected isolates. Moxalactam, doxycycline, minocycline, and clinafloxacin displayed the highest activity (greater than or equal to 98% susceptibility). Ticarcillin resistance (75%) was reverted by clavulanate in 258 of strains. Trimethoprim-sulfamethoxazole resistance was 26.2% (greater than or equal to4 [trimethoprim]/76 [sulfamethoxazole] mug/ml) and dropped to 11.1% when an 8/152-mug/ml breakpoint was applied based on its bimodal MIC distribution. Resistance was lower when unique strains were considered, because clonal organisms contribute to resistance.

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页码：1581 / 1584

页数：4

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