Photons to illuminate the universe of sugar diversity through bioarrays

被引:20
作者
Carroll, Gregory T. [1 ]
Wang, Denong [2 ]
Turro, Nicholas J. [1 ,3 ]
Koberstein, Jeffrey T. [3 ]
机构
[1] Columbia Univ, Dept Chem, New York, NY 10027 USA
[2] Stanford Univ, Sch Med, Carbohydrate Microarray Lab, Dept Genet, Stanford, CA 94305 USA
[3] Columbia Univ, Dept Chem Engn, New York, NY 10027 USA
基金
美国国家科学基金会;
关键词
photochemistry; bioarrays; surface chemistry;
D O I
10.1007/s10719-007-9052-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this mini-review, we summarize the photochemical approaches for developing high-throughput carbohydrate microarray technologies. Newly established methods for photo-immobilizing unmodified monosaccharides, oligosaccharides and polysaccharides onto photoactive surfaces and coupling of photoactive carbohydrates onto polymer surfaces are reviewed.
引用
收藏
页码:5 / 10
页数:6
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